Microbilogy Lecture Notes (ppt & pdf)

>> Saturday, March 27, 2010



An introduction to the structure of the bacterial cell


Bacterial identification in the diagnostic laboratory versus taxonomy.  
Taxonomic characterization of bacteria. Approaches to rapid diagnosis




Anaerobic and aerobic metabolism. Metabolism of sugars and fatty acids




Structure and synthesis of the cell walls of gram-positive and gram negative bacteria




The mode of action of beta-lactam antibiotics




The mode of action of antibacterial chemotherapeutic agents. Antibiotic susceptibility 
testing. The mechanisms by which bacteria express resistance to antibiotics





The general composition and structure of bacteriophage.
The infectious process and the lytic multiplication cycle.
The lysogenic cycle and its regulation




The mechanisms of gene transfer in bacteria. The nature of transposable
 genetic elements and plasmids. The significance of gene transfer, transposable 
genetic elements and plasmids




The structure and transcription of bacterial genes. The molecular mechanisms 
that bacteria use to regulate gene activity. Inducible and repressible operons. 
The molecular mechanisms involved in catabolite repression and attenuation. 
The ways bacteria regulate enzyme activity





Exotoxins and endotoxins, transmission, adhesion, immunopathology




Enterobacteriaceae, Vibrio, Campylobacter and Helicobacter 









Groups A, B and D  streptococcus, pathogenesis, diagnosis




Streptococcus and pneumonia, Staphylococcus infections, food poisoning, toxic shock




Syphilis, Lyme disease, leptospirosis, gonorrhea, meningitis




Clostridia, gas-gangrene, tetanus, botulism, pseudomonads




Mycobacterial diseases: tuberculois, Legionaires' disease, diphtheria, leprosy




Listeria, Francisella, Brucella, Bacillus and Yersinia Plague, Anthrax, Brucellosis, Listeriosis



Whooping cough, Hib disease



The morphological and physiological characteristics of the mycoplasmas. 
Pathogenesis of mycoplasma infections. Clinical syndromes associated with 
and the epidemiology, diagnosis and treatment of mycoplasma infections



Developmental cycle of chlamydia. Pathogenesis, epidemiology and clinical 
syndromes associated with chlamydia.



Interactions of the Rickettsia, Ehrlichia, Coxiella and Bartonella with the host cell. Pathogenesis, epidemiology and clinical syndromes associated with Rickettsia, Ehrlichia, Coxiella and Bartonella. Methods for treatment, prevention and control of rickettsial diseases.



Credits: University of South Carolina School Of Medicine

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